Network biology made easy
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INFORM

Discover Biological Insights

Explore a range of biological information. Make sense of your protein network with customizable annotations and visual cues. Highlight relevant disease pathways and uncover novel protein–protein interactions. Pinpoint which genes are statistically enriched across an array of biological processes.

INSPECT

Apply Your Data

Integrate your data to unlock deeper network insights. Expose differential gene expression with interactive visualisations. Store your data and easily switch between data sets. Save your analysis and visualisations for further inspection.

Experimental data
Workspaces

INTERFACE

Customize Your Environment

Tailor a project workspace and save your relevant networks. Apply views and annotations across projects. Easily share your findings and enable further discovery.

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Guest

The Interactome

Core Interactome

Protein information

Biological annotations

Fast enrichment analysis

Export network reports

5 protein interaction searches

3 annotation visualisations

Registered user Free

All guest features

Including the following upgrades:

Publish networks

1 experimental dataset

5 networks in workspace

5 protein interaction searches

5 annotation visualisations

2 custom annotations

License

All registered user features

Including the following upgrades:

Protein text mining

Export PPI information for networks up to 1000 proteins

Access to interaction evidence

10 experimental datasets

500 protein interaction searches

1000 networks in workspace

Unlimited annotation visualisations

Unlimited custom annotations

The Interactome

Protein Interaction Database

The The Interactome database of high confidence protein-protein interactions is an ideal resource forelucidation of biological processes involved in diseases and to aid drug development.

  • High-coverage map of human protein biology
  • Highly trustworthy interactions extracted by scoring +6M traceable entries of interaction evidence

All publications using ZS Revelen or The Interactome data must cite Li, Wernersson et al., Nat. Methods 2017.

See publication View 350+ citations
Protein Interaction Database

Data Sources

The following publications describe important data resources used for ZS Revelen and The Interactome

Nucleic Acids Res. 2003 Jan 1;31(1):248-50

BIND: the Biomolecular Interaction Network Database
Nucleic Acids Res. 2003 Jan 1;31(1):248-50

Bader GD, Betel D, Hogue CW

Nucleic Acids Res. 2016 Jan 4; 44(D1):D7-19. doi: 10.1093/nar/gkv1290. Epub 2015 Nov 28

Database resources of the National Center for Biotechnology Information
Nucleic Acids Res. 2016 Jan 4; 44(D1):D7-19. doi: 10.1093/nar/gkv1290. Epub 2015 Nov 28

NCBI Resource Coordinators

Nucleic Acids Res. 2009 Jan;37(Database issue):D5-15. doi: 10.1093/nar/gkn741. Epub 2008 Oct 21

Database resources of the National Center for Biotechnology Information
Nucleic Acids Res. 2009 Jan;37(Database issue):D5-15. doi: 10.1093/nar/gkn741. Epub 2008 Oct 21

Sayers EW, Barrett T, Benson DA, Bryant SH, Canese K, Chetvernin V, Church DM, DiCuccio M, Edgar R, Federhen S, Feolo M, Geer LY, Helmberg W, Kapustin Y, Landsman D, Lipman DJ, Madden TL, Maglott DR, Miller V, Mizrachi I, Ostell J, Pruitt KD, Schuler GD, Sequeira E, Sherry ST, Shumway M, Sirotkin K, Souvorov A, Starchenko G, Tatusova TA, Wagner L, Yaschenko E, Ye J

BMC Bioinformatics. 2009 Jun 16 ;10 Suppl 6:S3. doi: 10.1186/1471-2105-10-S6-S3

Databases of homologous gene families for comparative genomics

Penel S, Arigon AM, Dufayard JF, Sertier AS, Daubin V, Duret L, Gouy M, Perrière G

Nucleic Acids Res. 2016 Jan 4; 44(D1):D286-93. doi: 10.1093/nar/gkv1248. Epub 2015 Nov 17

eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences
Nucleic Acids Res. 2016 Jan 4; 44(D1):D286-93. doi: 10.1093/nar/gkv1248. Epub 2015 Nov 17

Huerta-Cepas J, Szklarczyk D, Forslund K, Cook H, Heller D, Walter MC, Rattei T, Mende DR, Sunagawa S, Kuhn M, Jensen LJ, von Mering C, Bork P

Lottenborgvej 26, 2800 Kongens Lyngby / Denmark